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Lecturer(s)
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Kanďár Roman, prof. Mgr. Ph.D.
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Štěpánková Šárka, Mgr. Ph.D.
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Course content
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Introduction to the biochemistry. Characteristic of living systems. Molecular components of cells. Biological membranes. Amino acids, peptides, proteins. Immunoglobulins, hemoproteins. Carbohydrates, monosaccharides, polysaccharides, glycoproteins. Lipids, structure. Fatty acids, triacylglycerols, phospholipids, steroids. Lipid bilayers. Lipoproteins, steroid. Nucleotides, nucleic acids. Enzymes. Vitamins. Cofactors and coenzymes. Enzymatic catalysis. Electron transfer and oxidative phosphorylation. The mitochondrion. Photosynthesis. Citric acid cycle, synthesis of acetyl-coenzyme A. Glycolysis, the pentose phosphate pathway. Fructose and galactose metabolism. Glycogen metabolism and gluconeogenesis. Lipid metabolism. Fatty acid oxidation, fatty acid biosynthesis, cholesterol metabolism. Amino acid metabolism, protein degradation. The urea cycle, breakdown of amino acids. Amino acids biosynthesis. Nucleotide metabolism. Synthesis of purine and pyrimidine nucleotides. Nucleotide degradation. Gene expression and replication.
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Learning activities and teaching methods
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Monologic (reading, lecture, briefing)
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Learning outcomes
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The students will learn the basic knowledge of biochemistry in English.
The student will acquire complex knowledge of metabolic processes in living organism in English.
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Prerequisites
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Not specified
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Assessment methods and criteria
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Oral examination
oral exam
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Recommended literature
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Donald Voet, Judith G. Voet. Biochemie. Victoria Publishing, 1995. ISBN 80-85605-44-9.
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Mathews C. K., van Holde K. E., Ahern K. G. Biochemistry, third edition, Addison.
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Voet D, Voet JG, Pratt CW, Charlotte W. Fundamentals of Biochemistry. John Willey & Sons, Inc., New York, 1999.
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