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Lecturer(s)
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Bílková Zuzana, prof. RNDr. Ph.D.
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Slováková Marcela, doc. Mgr. Ph.D.
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Course content
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Basic immunology Main components of immune system. Antigens, HLA molecules, genetic basis. Adhesive molecules, cytokines. Non-specific components: phagocytosis. Non-specific components: complement. Apoptosis. Inflammatory reaction, cells and humoral components. Specific immunity components: B and T cells. Processing and presentation of antigens, specific receptors. Forming of antibodies, primary and secondary reaction, regulation. Therapy of immune system: vaccination, immunological memory. Basic of Imunoanalytical Methods Antigens and antibodies, stuctures, functions and interactions. Principles of preparation of main types of antibodies. Immunoanalytical methods: immunoassays enzymatic, radioizotope, fluorescence, electrophoretic Immunoprecipitation, immunoagglutination, complement fixation. Lydyard Peter: Immunology, Garland Science 2011; chapters A to F. Daussant Jean: Introduction to Immunochemical techniques, Institute of chemical technology Prague 2007; chapters 1 and 2.
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Learning activities and teaching methods
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Dialogic (discussion, interview, brainstorming)
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Learning outcomes
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To obtain clear and solid knowledge about principles of human immune system, cells, tissues and molecules.
Student will be able to explain mechanisms of immunological defence to bacterias and viruses, and mechanisms of immune system after transplantation and in deficiences estates.
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Prerequisites
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unspecified
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Assessment methods and criteria
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Written examination
Written examination
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Recommended literature
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Daussant Jean, F.-Xavier Desvaux. Introduction to immunochemical techniques.. 2007.
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Gabriel Virella. Medical immunology. 2001. ISBN 0-8247-0550-5.
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Janeway, Ch. A. jr. Immunobiology, 6th ed., 2001.
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Klein, Jan; Hořejší, Václav. Immunology, 2nd ed., Oxford : Blackwell Science, 1997.
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Kuby, Janis. Immunology, 2nd ed., New York : W.H. Freeman, 1994.
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Peter Lydyard, Alex Whelan, Michael Fanger. Immunology. 2011. ISBN 978-0-415-60753-7.
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Roitt, I. M. Essential immunology (A), last edition.
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