| Course title | Fundamentals of Cytology and Biomaterial Applications |
|---|---|
| Course code | KBBV/C073 |
| Organizational form of instruction | Lecture |
| Level of course | Bachelor |
| Year of study | not specified |
| Semester | Summer |
| Number of ECTS credits | 6 |
| Language of instruction | Czech |
| Status of course | Compulsory |
| Form of instruction | Face-to-face |
| Work placements | This is not an internship |
| Recommended optional programme components | None |
| Lecturer(s) |
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| Course content |
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1st week: Introduction to cell biology - cell compartmentation. Cell membranes - structure, function, transport of substances. 2nd week: Cell nucleus - structure, function, nucleic acids, chromosomes, DNA synthesis, gene, genetic code. 3rd week: Endoplasmic reticulum, Golgi complex, cytoskeleton. Cell cycle and its regulation. 4th week: Mitochondria - structure, function, ATP formation, mitochondrial DNA. 5th week: Basic types of eukaryotic cells. Cell surface structures - adhesive molecules, intercellular junctions, protein structures. 6th week: Stem cells - classification, properties. Stem cell plasticity. Stem cell niches. 7th week: Cell death - classification (apoptosis, necrosis, autophagy, senescence). Malignant cell transformation. 8th week: Operation of a cell culture laboratory - material and technical security, hygiene, equipment. 9th week: Cell isolation, culture protocols - passaging of adherent and suspension cell lines. Culture conditions. In vitro cell differentiation. 10th week: Overview and properties of biomaterials - biocompatibility, biodegradability, immunogenicity, cytotoxicity. 11th week: Biomaterials for 2D and 3D cell line cultivation - natural vs. artificial scaffolds. 12th week: Decellularization and advanced methods of 3D cell culture cultivation. 13th week: Use of cell cultures in regenerative medicine and tissue engineering.
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| Learning activities and teaching methods |
| Monologic (reading, lecture, briefing) |
| Learning outcomes |
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The aim of the course is to familiarize students with the structure of the human cell and the structure and function of organelles. The course also includes a detailed introduction to the operation of a cell culture laboratory, including cell cultivation conditions and characterization of usable biomaterials that can be used in connection with cell cultivation. Students will also gain basic knowledge of regenerative medicine and tissue engineering.
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| Prerequisites |
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unspecified
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| Assessment methods and criteria |
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Written examination
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| Recommended literature |
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| Study plans that include the course |
| Faculty | Study plan (Version) | Category of Branch/Specialization | Recommended semester |
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