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Lecturer(s)
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Slováková Marcela, doc. Mgr. Ph.D.
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Bílková Zuzana, prof. RNDr. Ph.D.
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Course content
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Summary of basic immunology,cells and tissues involved in the immune response, major histocompatibility complex, acquired and specific immune response, humoral and cell-mediated immunity. The basis of clinical immunology focused to the hypersensitivity reactions, tolerance and autoimmunity, organ-specific and systemic autoimmune disease, immunohematology, immune system modulators, immunodeficiencies, infection of the immunocompetent cells, transplantation immunology, tumor immunology and malignancies of the immune system. All above mentioned sectiones are complemented by applied diagnostic methods.
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Learning activities and teaching methods
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Monologic (reading, lecture, briefing)
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Learning outcomes
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The aim of this subject is to develop the skills necessary to become an expert in diagnostic area of clinical medicine. The general goal is to develop the student in a flexible fashion adapted to the requirements of clinical practice. Laboratory training in a wide range of immunochemical techniques, their validation and precise interpretation of results is also considered part of the educational program.
Students know the basics about clinical immunology, diseases of human immune system, also the principle of all the basic tests used in clinical medicine for diagnosis in immunology, microbiology, allergology, transplantation immunology, immunohematology. To predict the complex of diagnostic tests and interpret the results of them.
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Prerequisites
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Student should know the basics from cellular biology, microbiology and immunology. C636 Immunology C501 Biology
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Assessment methods and criteria
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Oral examination, Written examination
Seminar work - ppt presentation (30%), written final test (50%), oral examination.
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Recommended literature
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Bartůňková J, Paulík M. Vyšetřovací metody v imunologii, Grada, 2005.
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Bartůňková J., Vernerová E. Imunologie a alergologie, Triton, Praha 2003.
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Fučíková T. Klinická imunologie v praxi, Galén, Praha 1995.
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Hořejší V., Bartůňková J. Základy imunologie. Triton, 1999, 2001.
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Johnstone A., Thorpe R. Immunochemistry in practice, Blackwell Science, 1996.
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Kopecký O. A KOL. Laboratorní vyšetření v klinické imunologii a alergologii , Garamon, Hradec Králové 2004.
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Phillips T. M. Analytical Techniques in Immunochemistry, Marcel Dekker inc., 1992.
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