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Lecturer(s)
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Holubová Jana, doc. RNDr. Ph.D.
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Course content
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1st week Chemical bonding, covalent bonding agents, VSEPR - extension. 2nd week Ionic bonds, lattice energy, Madelung's costant, ion stability, Faience's rules, Week 3 Bonding in solids-extension. Crystalline and non-crystalline state - long and short arrangement distance. Symmetry of crystals and crystal lattices, isomorphism, polymorphism, types of crystal lattices. Week 4 Thermochemistry + calculations Week 5 Acidity and alkalinity of substances Broenstedt-Lowry theory, factors influencing the strength of acids and bases. Buffer and salt solutions + calculations. Lewis theory of acids and bases, HSAB. Week 6 Equilibrium of redox processes, redox potentials. Electrolysis + basic calculations. Week 7 Boron, binding, properties, the most important compounds. Silicon, bond, properties, the most important compounds. 8th week Non-transition metals - metals of the 13th - 15th group. Transition metals - metals of the 4th and 5th groups. Week 9 Coordination compounds - nomenclature, binding and properties. Week 10 Overview of the chemistry of metals and non-metals in biological systems. 11th week Coordination compounds with biological activity, metalloenzymes, metalloproteins. Week 12 Elements and inorganic compounds in terms of medical application. Non-metals in medical application. 13th week Metals and their alloys for medical applications (Cr, Ti and their alloys, steels, precious metals and their alloys, amalgams, surface treatment and corrosion of metals)
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Learning activities and teaching methods
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Monologic (reading, lecture, briefing)
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Learning outcomes
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The student will gain advanced knowledge of inorganic chemistry. He gets orientation in the nomenclature, structure, binding and properties of complex compounds. The knowledge in the chemistry of non-metals and metal elements, which were not part of the lectures in the basic course will be supplemented.
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Prerequisites
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Completed courses General and inorganic chemistry I and II or basic orientation in general and inorganic chemistry.
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Assessment methods and criteria
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Oral examination, Written examination, Presentation
Continuous assessment - one writen test, elaboration of one seminar work Written and oral exam
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Recommended literature
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Alessio, Enzo. Bioinorganic medicinal chemistry. Weinheim: Wiley-VCH, 2011. ISBN 978-3-527-32631-0.
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C.E. Housecroft, A. G. Sharp. Anorganická chemie. Praha, 2014. ISBN 978-80-7080-872-6.
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Handlíř, Karel. Výpočty a cvičení z obecné a anorganické chemie II. Pardubice: Univerzita Pardubice, 2007. ISBN 978-80-7194-975-6.
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Richard J. D. Tilley. Understanding of Solids: The Science of Materials. John Wiley & Sons, Ltd., Velká Británie, 2004.
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