1st week: introduction to the subject: task formulation, literature, atomic nucleus, electron shell, periodic table of elements. 2nd week: chemistry of group 1 elements - alkali metals, biological function, sodium-potassium pump. 3rd week: chemistry of elements of 2 groups - alkaline earth metals, biological function x toxicity, calcium deposition in bones, chlorophyll (Mg) 4th week: chemistry of transition metal elements, biological function, metalloenzymes, glucose tolerance factor (Cr), superoxide dismutase (Mn), vitamin B12(Co) 5th week: hemoglobin and cytochromes (Fe), hemocyanin (Cu), Week 6: cis-platinum, history, mechanism of action, platinum cytostatics of next generations 7th week: non-platinum antitumor drugs, other possibilities of using transition metals as metallotherapeutics. 8th week: biological function of Zn (enzymatic cycles) x toxicity of metals (Cd, Hg) Week 9: non-metals, hydrogen, hydrogen bonding, theory of acids and bases. 11th week: chemistry of group 14 elements, biopolymers (Si), toxicity (Ge, Sn, Pb) 12th week: chemistry of group 15 elements, biological nitrogen fixation, toxicity (As, Sb, Bi) Week 13: chemistry of group 16 elements, biological function x toxicity, ozone, binding possibilities of sulfur in biological structures Week 14: chemistry of group 17 elements, biological function, oxygenic and hydrohalic acids, structure x acidity Seminars are held concurrently with the lectures, in which students practice the material discussed in the lectures and learn about basic chemical calculations (numbering equations, concentration calculations, dilution, stoichiometry and pH calculations).
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The course introduces students to basic ideas about the structure of the atom, chemical bonding, chemical reactions and solutions. Furthermore, the chemistry and properties of selected elements and compounds are discussed with regard to their function in biological systems or their toxicity. In the seminars, students learn basic chemical calculations and practically practice the material discussed in the lectures.
Understanding the relationship between structure and properties/reactivity of substances, biological function. Practical mastery of basic chemical calculations.
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