Lecturer(s)
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Pouzar Miloslav, prof. Ing. Ph.D.
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Course content
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1. Opening lecture ? interesting up-to day toxicological topic 2. Interaction of toxic substance with organism I - absorption a distribution 3. Interaction of toxic substance with organism II - biotransformation, excretion, recept. 4. Factors affecting effects of toxic substances 5. Experimental toxicology - modern methods of toxicological research 6. Nutrients a oxidative stress 7. Toxicology of heavy metals I - As, Hg 8. Toxicology of heavy metals II - Pb a Cd 9. Another toxic elements - Be, Al, Ni, Cr, Mn, Zn, Cu, Se, Ba, Tl, Ag 10. Toxicology of inorganic compounds of C 11. Toxicology of inorganic compounds of P, S a N 12. Toxicology of organic compounds I 13. Toxicology of organic compounds II 14. Carcinogens, mutagens and teratogens
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Learning activities and teaching methods
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Work with text (with textbook, with book)
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Learning outcomes
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The aim of lectures is to explain the basics of general and special toxicology with accent on problems occupational toxicology.
Students are well oriented in basics of general and experimental toxikology, they know toxic effects of elements and compounds selected as well as mechanisms of their toxicological activity and possibilities of toxicological risks reducing.
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Prerequisites
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Basic subject - there are not supposed any special skills or knowledge, only general competence of high school absolvent
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Assessment methods and criteria
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Didactic test
Exam test 100 %
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Recommended literature
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Linhart, Igor. Toxikologie : interakce škodlivých látek s živými organismy, jejich mechanismy, projevy a důsledky. Praha: Vysoká škola chemicko-technologická v Praze, 2012. ISBN 978-80-7080-806-1.
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