Course: Bioengineering

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Course title Bioengineering
Course code UECHI/C941
Organizational form of instruction Lecture + Seminar
Level of course Master
Year of study not specified
Semester Summer
Number of ECTS credits 4
Language of instruction Czech
Status of course Compulsory-optional, Optional
Form of instruction Face-to-face
Work placements This is not an internship
Recommended optional programme components None
Lecturer(s)
  • Mikulášek Petr, prof. Ing. CSc.
Course content
Specific problems of biotechnologies and bioengineering. Enzyme kinetics. Michaelis-Menten equation and determination of its parameters, inhibition of reaction rates. Microbial (Monod) kinetics. Inhibition, kinetic models of formation of product. Characteristics of flow of phases in apparatus for biotechnologies. Distribution of residence times of particles in reactor. Calculation of conversion degree of enzyme-catalysed reaction. Ideal mixer, reactor with plunger flow, conversion of enzymatic reaction in a cascade of ideal mixers. Bioreactors. Specification of enzyme and microbial reactions from the point of view of the reactor design; ways of operating bioreactors. Factors determining the choice of reactor type. Classification of bioreactors: the most usual types. Fermenters with pneumatic stirring. Fermenters with and without forced circulation of liquid. Fermenters with mechanical stirring. Basic hydrodynamic regimes of dispersing gases in fermenters, design parameters of fermenters. Reactors with immobilised enzymes of cells. Membrane bioreactors. Enzyme reactors and membrane fermenters. Classic and non-traditional separation methods in biotechnologies. Membrane separations, separation by means of affinity chromatography, extraction with liquefiable and supercritical gases. Special problems of bioreactors. Prices of reactors and their shapes and specifics of fermentation process, defoaming, sterilisation. Environmental engineering. Technology of treatment of some types of wastewater.

Learning activities and teaching methods
Monologic (reading, lecture, briefing), Work with text (with textbook, with book)
Learning outcomes
The course covers the principles of biotechnologies from a chemical engineering point of view. The emphasis is given on examining the systems and components that are common to most or all biotechnology production processes.
The subject forms a continuation to knowledge acquired in chemical engineering and informs students about the basics enabling a more quantitative description of processes taking place with participation of enzymes, micro-organisms and tissue cultures (bioreactor technique, modern separation methods, basics of modern control of bioreactors, selected specifics of laboratory fermenters, and applications of biotechnologies to protection of environment).
Prerequisites
Basic physical chemistry, Chemical engineering I

Assessment methods and criteria
Oral examination, Written examination

There is an oral examination. Primary form of exam is the debate about selected themes. Level of acquired knowledge, conceptions and application acquirements is examined. Knowledge is examined by test during semester and its result is included into total classification.
Recommended literature
  • DORAN P.M. Bioprocess Engineering Principles. Academic Press, London, 1995.
  • Kaštánek F. Bioinženýrství. Academia, Praha, 2000.


Study plans that include the course
Faculty Study plan (Version) Category of Branch/Specialization Recommended year of study Recommended semester
Faculty: Faculty of Chemical Technology Study plan (Version): Chemical Engineering (2013) Category: Engineering chemistry and chemistry of silicates - Recommended year of study:-, Recommended semester: Summer
Faculty: Faculty of Chemical Technology Study plan (Version): Chemical Engineering (2015) Category: Engineering chemistry and chemistry of silicates - Recommended year of study:-, Recommended semester: Summer
Faculty: Faculty of Chemical Technology Study plan (Version): Chemical Engineering (2013) Category: Engineering chemistry and chemistry of silicates 1 Recommended year of study:1, Recommended semester: Summer
Faculty: Faculty of Chemical Technology Study plan (Version): Economy and Management of Chemical and Food Industry (2015) Category: Engineering chemistry and chemistry of silicates - Recommended year of study:-, Recommended semester: Summer
Faculty: Faculty of Chemical Technology Study plan (Version): Economy and Management of Chemical and Food Industry (2013) Category: Engineering chemistry and chemistry of silicates - Recommended year of study:-, Recommended semester: Summer
Faculty: Faculty of Chemical Technology Study plan (Version): Environment Protection (2016) Category: Ecology and environmental protection - Recommended year of study:-, Recommended semester: Summer
Faculty: Faculty of Chemical Technology Study plan (Version): Chemical Engineering (2016) Category: Engineering chemistry and chemistry of silicates 1 Recommended year of study:1, Recommended semester: Summer
Faculty: Faculty of Chemical Technology Study plan (Version): Environment Protection (2013) Category: Ecology and environmental protection - Recommended year of study:-, Recommended semester: Summer
Faculty: Faculty of Chemical Technology Study plan (Version): Environment Protection (2015) Category: Ecology and environmental protection - Recommended year of study:-, Recommended semester: Summer
Faculty: Faculty of Chemical Technology Study plan (Version): Economy and Management of Chemical and Food Industry (2016) Category: Engineering chemistry and chemistry of silicates - Recommended year of study:-, Recommended semester: Summer
Faculty: Faculty of Chemical Technology Study plan (Version): Chemical Engineering (2016) Category: Engineering chemistry and chemistry of silicates - Recommended year of study:-, Recommended semester: Summer
Faculty: Faculty of Chemical Technology Study plan (Version): Chemical Engineering (2015) Category: Engineering chemistry and chemistry of silicates 1 Recommended year of study:1, Recommended semester: Summer