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Lecturer(s)
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Teichmanová Kateřina, Ing. Ph.D.
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Imramovský Aleš, prof. Ing. Ph.D.
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Hrdina Radim, prof. Ing. CSc.
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Course content
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Course contents, titles of individual chapters (lectures): Week 1. Calculations and description of chemical reactors used in organic technology. Week 2. Physical transformation. 3rd week. Processing of basic C raw materials for production of organic chemicals, oil refining and petrochemical processes. Week 4. Catalysis (homogeneous, heterogeneous) in organic production. Week 5. Production and processing of C2, C3, C4 fractions. 6th week. Hydrogenation and dehydrogenation. 7th week. Oxidation in gaseous and liquid phase, gas phase oxidation with heterogeneous catalysis. 8th week. Halogenation of aliphatic and aromatic hydrocarbons, dehydrohalogenation 9th week Sulfonation of aliphatic and aromatic compounds, nitration and nitrosation of aromatic compounds 10th week. Alkylation, acylation, isomerization, oligomerization, hydration. 11th week. Production based on nucleophilic substitution. Week 12. Industrial synthesis based on CO and CO2. 13th week. Diazotation, coupling - production of azo-compounds. Production equipment, technology.
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Learning activities and teaching methods
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unspecified
- Preparation for a partial test
- 39 hours per semester
- Preparation for a final test
- 39 hours per semester
- Contact teaching
- 39 hours per semester
- Preparation for an exam
- 78 hours per semester
- Home preparation for classes
- 39 hours per semester
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Learning outcomes
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The aim of the course is to teach students the technology of organic substances, organic specialties such as pharmaceuticals, medical devices, including processing of basic C raw materials and semi-finished products. Teaching is conducted (lectured) in a processing manner, where the content of individual lectures is as follows. Week 1. Calculations and description of chemical reactors used in organic technology. Week 2. Physical transformation. 3rd week. Processing of basic C raw materials for production of organic chemicals, oil refining and petrochemical processes. Week 4. Catalysis (homogeneous, heterogeneous) in organic production. Week 5. Production and processing of C2, C3, C4 fractions. 6th week. Hydrogenation and dehydrogenation. 7th week. Oxidation in gaseous and liquid phase, gas phase oxidation with heterogeneous catalysis. 8th week. Halogenation of aliphatic and aromatic hydrocarbons, dehydrohalogenation 9th week Sulfonation of aliphatic and aromatic compounds, nitration and nitrosation of aromatic compounds 10th week. Alkylation, acylation, isomerization, oligomerization, hydration. 11th week. Production based on nucleophilic substitution. Week 12. Industrial synthesis based on CO and CO2. 13th week. Diazotation, coupling - production of azo-compounds. Production equipment, technology.
After completing the course, the students have a basic idea of the technology of pharmaceutical compounds. They are able to perform basic technological calculations and propose a method of production of organic compounds from starting carbon raw materials, fossil and natural ones.
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Prerequisites
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Lecturer must have basics of university mathematics, mainly differential and integral calculus, basics of physics, inorganic and organic chemistry, basics of physical chemistry all at the level of successfully completed bachelor study.
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Assessment methods and criteria
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Oral examination, Written examination
Before the oral exam, the student must pass a semester written exam, which must be at least 33% points in order to pass to the oral exam.
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Recommended literature
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Hanika, J. Farmaceutické inženýrství. Praha: VŠCHT Praha, 2013..
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Hrdina, R., Machalický O. Organická technologie. Dostupné v systému STAG. Univerzita Pardubice, aktuální verze.
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Mall, I. D. Petrochemical Process Technology. Macmillan India Limited, 2006..
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Weissermel, K., Arpe, H. J. Industrial Organic Chemistry. Weinheim:Wiley-VCH, 2003..
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