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Lecturer(s)
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Fusek Josef, prof. MUDr. DrSc.
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Pohanka Miroslav, prof. RNDr. PhD., DSc.
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Course content
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The subject of pharmacology, basic concepts. Basics of pharmacokinetics and of pharmacodynamics. Research and development of new medicines. Overview of medicines affecting the autonomic nervous system. Overview of medicines that affect pain. Medicines affecting the heart and blood vessels. Medicines used for diseases of the respiratory system, gastrointestinal system medicines. Medicines used for kidney diseases. Overview of antibiotics and chemotherapy. Overview of cytostatic agents. Disinfectants and antiseptics. Addiction to medicines, substance dependence. Basics of toxicology. Types of chemicals, exposure, selective intoxication. Relation dose - response, threshold dose, synergism. Absorption, distribution, metabolism and excretion of toxic substances. Types of organism´s response to a toxic substance. Toxicology of plant and animal toxins. Analytical Toxicology. Forensic toxicology. Medicinal and substance intoxication, treatment options, assignment presentations.
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Learning activities and teaching methods
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Monologic (reading, lecture, briefing), Work with text (with textbook, with book)
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Learning outcomes
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The aim of the course is to acquaint students with the basics of general pharmacology, special pharmacology and toxicology of drugs and important chemicals relevant for practical use and application in other subjects.
Students will master the basics of toxicology of chemical noxious agents, poisons, and toxins on the human body.
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Prerequisites
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unspecified
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Assessment methods and criteria
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Didactic test
Mandatory 80% attendance at lectures. Prepare and present a PC-specified theme with the content of providing medical assistance for drug overdose or chemical noxous exposure.
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Recommended literature
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FUSEK, J., HERINK, J., PLESKOT, O. Obecná farmakologie. Pardubice: Univerzita Pardubice, 2018.
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LÜLLMANN, H.; MOHR, K.; HEIN, L. Barevný atlas farmakologie. Praha: Grada, 2012.
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Pohanka, M. Přehled toxikologie: Učební texty. Hradec Králové: Fakulta vojenského zdravotnictví Univerzity obrany, 2013. ISBN 978-80-7231-353-2.
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Prokeš, Jaroslav. Základy toxikologie : obecná toxikologie a ekotoxikologie. Praha: Galén, 2005. ISBN 80-7262-301-X.
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