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Lecturer(s)
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Královec Karel, RNDr. Ph.D.
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Moťková Petra, Ing. Ph.D.
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Stříbrná Lucie, Mgr. Ph.D.
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Course content
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Chemical composition of cell. Cell theory. Bio membranes (structure, composition). Internal Cell membrane system. Semiautonomous organells (mitochondrions, chloroplasts). Cytoskeleton, microtubules, microfilaments, intermediate filaments, cell and organelle movement. Nucleus-composition and function, structure of chromosomes, disruption of number and structure of chromosomes. Structure and function of DNA, replication, realization of genetic information, transcription, translation. Cell reproduction, cell cycle,mitosis, cytokinesis. Malignant cell transformation, damage and cell death, necrosis and apoptosis. Viruses, characteristic, structure and shape of virions. Virus reproduction in host cells, classification of viruses. Prions. Cell and its neighbourhood, inter cell communication, adhesion, recognition of cells, extracellular matrix. Reproduction of organism, asexual, sexual reproduction, meiosis, spermatogenesis, oogenesis, semination, ontogenesis. Evolution, micro and macroevolution.
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Learning activities and teaching methods
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Monologic (reading, lecture, briefing), Projection
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Learning outcomes
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The aim of the course is to familirize the students with cell biology of different types (eukaryotic cells and prokaryotic cells). The aim is to create a knowledge base for other biologically and medically oriented related subjects.
Students will be able to understand well the cell biology, signinficantly metabolism and (patho)physiology of the cell, also the basic virology and mikrobiology will be presented. Biology is prerequisite for biochemistry, molecular biology, physiology, immunology etc.
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Prerequisites
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unspecified
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Assessment methods and criteria
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Written examination
Written exam. Students must answer more than 60 % questions.
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Recommended literature
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Alberts, B. a kol. Základy buněčné biologie. Espero Publishing, Ústí n.L. 2005.
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Kubišta, V. Buněčné základy životních dějů. Scientia, Praha 1998.
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Nečas, O. a kol. Obecná biologie pro lékařské fakulty. H&H, Jinočany 2000.
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Rosypal S. a kol. Nový přehled biologie. Scientia, Praha 2003.
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Rosypal, S. Úvod do molekulární biologie I., II., III., a IV. díl. Brno 1998-2002.
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Závodská, Radka. Biologie buněk. Praha. 2006.
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