Course: Biochemistry I

« Back
Course title Biochemistry I
Course code KBBV/C602
Organizational form of instruction Lecture
Level of course Bachelor
Year of study not specified
Semester Winter
Number of ECTS credits 4
Language of instruction Czech
Status of course Compulsory
Form of instruction Face-to-face
Work placements This is not an internship
Recommended optional programme components None
Lecturer(s)
  • Korecká Lucie, doc. RNDr. Ph.D.
Course content
1. Historical development of biochemistry. Characteristics of living systems - composition, organization, function. 2. Cell - prokaryotic and eukaryotic, differences, structure, organelles. Membranes, composition, function. Water and its biochemical significance in the organism. 3. Amino acids, peptides and proteins - structure, function, meaning. Plant and animal proteins, complex proteins. 4. Enzymes - nomenclature, structure, function, basic division. Coenzymes - basic division and function of important coenzymes (ATP, NAD, FAD, SAM, PAPS, CoA) 5. Kinetics of enzyme reactions - theoretical basis, Michaelis-Menten equations, linearization. Specificity of enzymes. Enzymatic inhibition 6. Nucleotides and nucleic acids - structure and significance, replication, translation and transcription. Posttranslational modifications. 7. Carbohydrates - basic division, structure and function. Carbohydrate metabolism - anaerobic glycolysis, ethanol fermentation, muscle and liver glycogenolysis Carbohydrate degradation 8. Lipids - structure and function. Lipid metabolism. Fatty acids, phospholipids, lipoproteins, cholesterol. 9. Nitrogen metabolism - degradation and biosynthesis of amino acids, ornithine cycle, degradation nucleotide base. 10. Principles of metabolism and energy transformation, bioenergetics 11. Citrate and glyoxylate cycle - significance, function, energy balance 12. Aerobic and anaerobic respiration - respiratory chain, oxidative phosphorylation 13. Photosynthesis - photosynthetic apparatus, dyes, Calvin cycle

Learning activities and teaching methods
Monologic (reading, lecture, briefing), Dialogic (discussion, interview, brainstorming), Řízená praxe
Learning outcomes
In frame of subject Biochemistry student obtain th basic knowledge in biochemistry of alive organisms with a view of anabolism and katabolism. Biochemical processes are described on molecular level and demonstrated with chemical reactions with use of enzymatic catalysis.
According the subject, student will get a komplexe knowledges about composition course of alive organisms and about basic metabolic processes.
Prerequisites
Student should dispose with knowledges from subjects Biology and Organic chemistry

Assessment methods and criteria
Oral examination, Written examination

written test - 60% + oral examination. To take the oral examination, it is necessary to achieve the 60% specified in the written part.
Recommended literature
  • Kodíček M. Biochemické pojmy - výkladový slovník. Praha, 2004.
  • Korecká, Lucie. Obecná biochemie : pro speciální chemicko-biologické obory. Pardubice: Univerzita Pardubice, 2012. ISBN 978-80-7395-470-3.
  • Murray, Robert K. Robert Kincaid. Harperova biochemie. Jinočany: H & H, 2002. ISBN 80-7319-013-3.
  • Vodrážka Z. Biochemie. Praha: Academia, 1999.


Study plans that include the course
Faculty Study plan (Version) Category of Branch/Specialization Recommended year of study Recommended semester