Course: Laboratory of Biochemistry

« Back
Course title Laboratory of Biochemistry
Course code KBBV/C638
Organizational form of instruction Lesson
Level of course Bachelor
Year of study 2
Semester Winter
Number of ECTS credits 2
Language of instruction Czech
Status of course Compulsory
Form of instruction Face-to-face
Work placements This is not an internship
Recommended optional programme components None
Lecturer(s)
  • Morávek Ondřej, Mgr.
  • Štěpánková Šárka, Mgr. Ph.D.
Course content
Labour protection in biochemical lab, fire safety. Volume admeasurement, pipetting test, precision. Buffers, pH measurement. Aminoacids - determination of absorption maximum and molar absorption coefficient of chosen aminoacids, quantitative determination of aminoacids Proteins - determination of total protein using biuret reaction, precipitation of proteins by inorganic acids, organic solutions and inorganic salts.. Qualitative determination of saccharides. Quantitative determination of glucose. Lipids - determination of cholesterol in oils. Preparative chromatography of serum lipids and their quantification. Kinetics of enzymatic reaction, determination of Michaelis constant of urease. Determination of urea concentration in human serum. Determination of IC50 of butyrylcholinesterase inhibitors. Determination of vitamin A and C. Final test.

Learning activities and teaching methods
Laboratory work
Learning outcomes
The aim is to improve practical competency of student for application measuring physical and chemical properties of substrates, enzymes, vitamins, hormones and nucleic acids.
Student will be able to work in laboratories of biochemistry including centrifugation, extraction, protein precipitation, analytical and preparative chromatography, HPLC, spectrophotometric measurements. Student can to statistically interpret obtained results.
Prerequisites
not specified

Assessment methods and criteria
Written examination

credit test
Recommended literature
  • návody IS STAG. .
  • Štěpánková Š., Královcová P., Kanďár R. Laboratorní cvičení z obecné a klinické biochemie (druhé doplněné vydání). Pardubice: Univerzita Pardubice, 2018. ISBN 978-80-7560-174-2.
  • Štěpánková, Žáková, Kanďár. Laboratorní cvičení z obecné a klinické biochemie. Pardubice. 2022.


Study plans that include the course
Faculty Study plan (Version) Category of Branch/Specialization Recommended year of study Recommended semester