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Lecturer(s)
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Kanďár Roman, prof. Mgr. Ph.D.
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Course content
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Inherited metabolic disorders. Carbohydrate metabolism disorders. Amino acid metabolism disorders. Lipid metabolism disorders. Heme synthesis and degradation disorders. Purine and pyrimidine metabolism disorders. Mitochondrial diseases. Biochemistry of tumors. Neurodegenerative disease. Oxidative stress.
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Learning activities and teaching methods
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Monologic (reading, lecture, briefing)
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Learning outcomes
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The subject introduces the student to knowledge in the field of pathobiochemistry. It builds on the knowledge of biochemistry.
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Prerequisites
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unspecified
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Assessment methods and criteria
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Oral examination
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Recommended literature
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Eckhard Lammert; Martin Zeeb. Metabolism of Human Diseases. Organ Physiology and Pathophysiology. Wien: Austria, 2014. ISBN 978-3-7091-0714-0.
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József Mandl; Raymund Machovic; Miklós Csala. Medical pathobiochemistry. Budapest: Hungary, 2014. ISBN 9789632264073.
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Masopust, Jaroslav. Patobiochemie metabolických drah. Praha: Univerzita Karlova, 1999. ISBN 80-238-4589-6.
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Miroslav Ledvina, Roman Kanďár. Přehled patobiochemie. Pardubice: Univerzita Pardubice, 2001. ISBN 80-7194-399-1.
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Roman Kanďár. Vybrané kapitoly z obecné biochemie, klinické biochemie a pathobiochemie. Pardubice: Univerzita Pardubice, 2015. ISBN 978-80-7395-964-7.
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Toshitaka Oohashi; Hirokazu Tsukahara; Francesco Ramirez; Chad L. Barber; Fumio Otsuka. Human Pathobiochemistry. From Clinical Studies to Molecular Mechanisms. Singapore: Singapore, 2019. ISBN 978-981-13-2976-0.
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