Course: Basic Pharmacokinetics

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Course title Basic Pharmacokinetics
Course code KFCH/C320
Organizational form of instruction Lecture + Seminar
Level of course Bachelor
Year of study 3
Frequency of the course every winter semester, 1 x pro week
Semester Winter
Number of ECTS credits 3
Language of instruction Czech
Status of course Compulsory-optional
Form of instruction Face-to-face
Work placements This is not an internship
Recommended optional programme components None
Lecturer(s)
  • Komersová Alena, doc. Ing. Ph.D.
Course content
Basic conceptions, simple one-compartment pharmacokinetical models, renal drug elimination, metabolite pharmacokinetics, nonlinear pharmacokinetics, multicompartment pharmacokinetic models, pharmacokinetics following administration by intermittent intravenous infusion, pharmacokinetics - pharmacodynamics relationship.

Learning activities and teaching methods
Work with text (with textbook, with book)
Learning outcomes
The goal of the object is to obtain the basic knowledge about what the body is making with the drug after its administration (pharmacokinetics), what the drug is then making with the body (pharmacodynamics) and how to describe this behaviour on the basis of the laws of the formal reaction (chemical) kinetics, when the amount and the mode of the application of the drug are known
After graduation of the object the student will have the basic knowledge about the mutual behaviour of the living organism and the used drug with the possibility to describe and therefore to predict and control it to a certain extent.
Prerequisites
The knowledge of the reaction (chemical) kinetics.

Assessment methods and criteria
unspecified
Written and oral exam (questions and calculations)
Recommended literature
  • Hedaya M.A.:. Basic Pharmacokinetics. CRC Press, Taylor & Francis Group, Boca Raton, USA,, 2007.
  • Kodíček M., Karpenko V. Biofyzikální chemie, Academia Praha 1977.
  • Komers K., Čegan A., Komersová A., Machek J. Biofyzikální chemie. Univerzita Pardubice, 2003.


Study plans that include the course
Faculty Study plan (Version) Category of Branch/Specialization Recommended year of study Recommended semester
Faculty: Faculty of Chemical Technology Study plan (Version): Farmacochemistry and Medicinal Materials (2016) Category: Engineering chemistry and chemistry of silicates 3 Recommended year of study:3, Recommended semester: Winter
Faculty: Faculty of Chemical Technology Study plan (Version): Farmacochemistry and Medicinal Materials (2014) Category: Engineering chemistry and chemistry of silicates 3 Recommended year of study:3, Recommended semester: Winter
Faculty: Faculty of Chemical Technology Study plan (Version): Farmacochemistry and Medicinal Materials (2013) Category: Engineering chemistry and chemistry of silicates 3 Recommended year of study:3, Recommended semester: Winter
Faculty: Faculty of Chemical Technology Study plan (Version): Farmacochemistry and Medicinal Materials (2015) Category: Engineering chemistry and chemistry of silicates 3 Recommended year of study:3, Recommended semester: Winter