Course: Toxicology

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Course title Toxicology
Course code UECHI/C005
Organizational form of instruction Lecture
Level of course Bachelor
Year of study 1
Semester Winter
Number of ECTS credits 3
Language of instruction Czech
Status of course Compulsory
Form of instruction Face-to-face
Work placements This is not an internship
Recommended optional programme components None
Lecturer(s)
  • Pouzar Miloslav, prof. Ing. Ph.D.
Course content
1. Opening lecture ? interesting up-to day toxicological topic 2. Interaction of toxic substance with organism I - absorption a distribution 3. Interaction of toxic substance with organism II - biotransformation, excretion, recept. 4. Factors affecting effects of toxic substances 5. Experimental toxicology - modern methods of toxicological research 6. Nutrients a oxidative stress 7. Toxicology of heavy metals I - As, Hg 8. Toxicology of heavy metals II - Pb a Cd 9. Another toxic elements - Be, Al, Ni, Cr, Mn, Zn, Cu, Se, Ba, Tl, Ag 10. Toxicology of inorganic compounds of C 11. Toxicology of inorganic compounds of P, S a N 12. Toxicology of organic compounds I 13. Toxicology of organic compounds II 14. Carcinogens, mutagens and teratogens

Learning activities and teaching methods
Dialogic (discussion, interview, brainstorming), Work with text (with textbook, with book), Projection
Learning outcomes
The aim of lectures is to explain the basics of general and special toxicology with accent on problems occupational toxicology.
Students are well oriented in basics of general and experimental toxikology, they know toxic effects of elements and compounds selected as well as mechanisms of their toxicological activity and possibilities of toxicological risks reducing.
Prerequisites
Basic subject - there are not supposed any special skills or knowledge, only general competence of high school absolvent

Assessment methods and criteria
Didactic test

Exam test 100 %
Recommended literature
  • Hodgson, Ernest . A Textbook of modern toxicology. Hoboken: Wiley-Interscience, 2004. ISBN 0-471-26508-X.
  • Kupec J. Toxikologie. VUT Zlín, 1999.
  • Linhart, Igor. Toxikologie : interakce škodlivých látek s živými organismy, jejich mechanismy, projevy a důsledky. Praha: Vysoká škola chemicko-technologická v Praze, 2012. ISBN 978-80-7080-806-1.
  • Matrka M., Rusek V. Průmyslová toxikologie. VŠCHT Pardubice, 1991.
  • Paleček J., Linhart I., Horák J. Toxikologie a bezpečnost práce v chemii. VŠCHT Praha, 1996.
  • Rusek V. Základy toxikologie a úvod do problematiky hygieny a bezpečnosti práce v chemické laboratoři. Univerzita Pardubice, 2001.


Study plans that include the course
Faculty Study plan (Version) Category of Branch/Specialization Recommended year of study Recommended semester
Faculty: Faculty of Chemical Technology Study plan (Version): Clinical Biology and Chemistry (2014) Category: Special and interdisciplinary fields 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Chemical Technology Study plan (Version): Chemistry and Technical Chemistry (2013) Category: Engineering chemistry and chemistry of silicates 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Chemical Technology Study plan (Version): Clinical Biology and Chemistry (2016) Category: Special and interdisciplinary fields 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Chemical Technology Study plan (Version): Chemistry and Technical Chemistry (2016) Category: Engineering chemistry and chemistry of silicates 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Chemical Technology Study plan (Version): Chemistry and Technical Chemistry (2015) Category: Engineering chemistry and chemistry of silicates 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Chemical Technology Study plan (Version): Clinical Biology and Chemistry (2013) Category: Special and interdisciplinary fields 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Chemical Technology Study plan (Version): Clinical Biology and Chemistry (2015) Category: Special and interdisciplinary fields 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Chemical Technology Study plan (Version): Chemistry and Technical Chemistry (2014) Category: Engineering chemistry and chemistry of silicates 1 Recommended year of study:1, Recommended semester: Winter