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Lecturer(s)
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Drabina Pavel, doc. Ing. Ph.D.
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Course content
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Principles of organic stereochemistry. Mathematical description of molecules, models. Static stereochemistry: Isomerism, symmetry, conformation, stereochemistry of alicyclic, cyclic, fused and bridged ring systems, chirality, optical activity and optical stereoisomerism, physical and spectral properties of stereoisomers. Dynamic stereochemistry: addition reactions, elimination reactions, substitution reactions, rearrangements, pericyclic reactions. Synthesis of chiral compounds, asymmetric catalysis.
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Learning activities and teaching methods
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Monologic (reading, lecture, briefing), Skills training
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Learning outcomes
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How to describe molecules as spatial objects and to gain knowledge on physical and chemical properties of the chemical compounds.
Knowledge of physical, chemical and biological properties related with molecular spatial arrangement.
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Prerequisites
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Knowledge of organic chemistry within the scope of former courses.
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Assessment methods and criteria
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Oral examination
Understanding and knowledge Organic Chemistry.
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Recommended literature
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Červinka O. a kol.:. Chemie organických sloučenin, díl 1. SNTL, Praha 1985..
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Červinka O.:. Enantioselektivní reakce v organické chemii. 1985, Academia, Praha..
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Eliel E. S.:. Stereochemie uhlíkatých sloučenin. 1970, Academia, Praha..
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Fišer J.:. Úvod do molekulové symetrie: aplikace teorie grup v chemii. 1980, SNTL, Praha..
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Potapov M. V.:. Stereochemie. 1986, SNTL, Praha..
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Ramsay O. B:. Stereochémia. Univerzita Komenského, Bratislava 2000..
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