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Lecturer(s)
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Drabina Pavel, doc. Ing. Ph.D.
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Course content
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Structure of biopolymers. Survey, preparation and reaction of amino-acids. Preparation and structure of peptides and proteins. Survey and reaction of monosaccharides. Chemistry of disaccharides and polysaccharides. Chemistry of lipids. Chemistry of nucleosides, nucleotides and nucleic acids. Classification, biosynthesis and using of alkaloids. Classification, biosynthesis and function of terpenoids. Chemistry of steroids. Water-soluble vitamins. Fat-soluble vitamins.
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Learning activities and teaching methods
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Monologic (reading, lecture, briefing), Work with text (with textbook, with book), Projection
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Learning outcomes
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The aim of course is to extend the student`s knowledge in area of natural compounds. The course units are focused on tasks of preparation, structure and chemical and biological properties of peptides, proteins, saccharides, lipids, vitamins, nucleic acid, alkaloids, terpenoids and steroids. Each type of these compounds is introduced and their properties, preparation and chemical behavior are lectured.
The students are able to understand basic processes proceeding in living systems. They should gain the knowledge from synthesis, structure, biological and chemical properties of natural compounds.
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Prerequisites
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The basic knowledge of organic chemistry (especially nomenclature, stereochemistry, reaction mechanisms and reactivity of organic compounds) is necessary for passing of the course unit.
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Assessment methods and criteria
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Oral examination, Written examination
Graduation of course unit "Organic chemistry I - C008"
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Recommended literature
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" MACHÁČEK V., PANCHARTEK J., PYTELA O.:. Organická chemie, 2. část, 2. vydání, Univerzita Pardubice 1998..
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ČERVINKA O., DĚDEK V., FERLES M.:. Organická chemie, SNTL, Praha 1969..
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DOSTÁL J. A KOL.:. Lékařská chemie II - bioorganická chemie, MU, Brno 2005..
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Drabina P. Bioorganická chemie. Pardubice, 2020. ISBN 978-80-7560-316-6.
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KARLSON P.:. Základy biochemie, Academia, Praha 1981..
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VODRÁŽKA Z., KRECHL J.:. Bioorganická chemie, SNTL, Praha 1991..
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WAISSER K.:. Bioorganická chemie, Karolinum, Praha 1997..
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