| Course title | Organic Reactions Mechanisms |
|---|---|
| Course code | UOCHT/C550 |
| Organizational form of instruction | Lecture |
| Level of course | Master |
| Year of study | 1 |
| Semester | Summer |
| Number of ECTS credits | 5 |
| Language of instruction | Czech |
| Status of course | Compulsory-optional |
| Form of instruction | Face-to-face |
| Work placements | This is not an internship |
| Recommended optional programme components | None |
| Lecturer(s) |
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| Course content |
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Introduction. Stereochemistry of molecules. Stereochemistry of dynamic processes. Conformations, cyclic molecules, stereoelectronic effects. Study and description of reaction mechanisms. Basic mechanistic principles. Isotope effect. Reaction intermediates. Description of SN mechanisms, intermediate mechanisms. Ionic pairs. Carbenium ions. Neighbouring group participation. Mechanisms SNAr. SET.Reactions of the group C=X with nucleophiles. More O´Ferral diagrams. Acid-base catalysis. Nucleophilic substitution on the atom H, acidity, basicity. C-acids and carbanions. SEAr. Electrophilic addition. Eliminations. Reactions of radicals. Pericyclic reactions. Cycloadditions. Dipolar cycloadditions. Sigmatropic rearrangements.
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| Learning activities and teaching methods |
| Monologic (reading, lecture, briefing) |
| Learning outcomes |
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The aim of the course unit is to learn students through knowledges of reaction mechanisms to predict reaction paths and to set out reaction conditions, i.e. to learn students use the theoretical knowledges in synthetic practice.
Students will be able to solve synthetic problems of organic chemistry using knowledges of organic reactions mechanisms. |
| Prerequisites |
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Organic chemistry and Basic of organic synthesis.
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| Assessment methods and criteria |
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Oral examination, Written examination
One checking test will be written during the term, whose result will be included in the whole classification of the subject. The main exam is oral and the topic of the exam is discussion about the selected reaction mechanisms, the possibilities of their proving or disproving and the possibilities of their utilisation. |
| Recommended literature |
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| Study plans that include the course |
| Faculty | Study plan (Version) | Category of Branch/Specialization | Recommended semester | |
|---|---|---|---|---|
| Faculty: Faculty of Chemical Technology | Study plan (Version): Analytical Chemistry (2013) | Category: Chemistry courses | 1 | Recommended year of study:1, Recommended semester: Summer |
| Faculty: Faculty of Chemical Technology | Study plan (Version): Analytical Chemistry (2015) | Category: Chemistry courses | 1 | Recommended year of study:1, Recommended semester: Summer |
| Faculty: Faculty of Chemical Technology | Study plan (Version): Organic Chemistry (2015) | Category: Engineering chemistry and chemistry of silicates | 1 | Recommended year of study:1, Recommended semester: Summer |
| Faculty: Faculty of Chemical Technology | Study plan (Version): Technical Physical Chemistry (2016) | Category: Engineering chemistry and chemistry of silicates | 1 | Recommended year of study:1, Recommended semester: Summer |
| Faculty: Faculty of Chemical Technology | Study plan (Version): Organic Chemistry (2013) | Category: Engineering chemistry and chemistry of silicates | 1 | Recommended year of study:1, Recommended semester: Summer |
| Faculty: Faculty of Chemical Technology | Study plan (Version): Organic Chemistry (2016) | Category: Engineering chemistry and chemistry of silicates | 1 | Recommended year of study:1, Recommended semester: Summer |
| Faculty: Faculty of Chemical Technology | Study plan (Version): Technical Physical Chemistry (2013) | Category: Engineering chemistry and chemistry of silicates | 1 | Recommended year of study:1, Recommended semester: Summer |
| Faculty: Faculty of Chemical Technology | Study plan (Version): Analytical Chemistry (2016) | Category: Chemistry courses | 1 | Recommended year of study:1, Recommended semester: Summer |
| Faculty: Faculty of Chemical Technology | Study plan (Version): Technical Physical Chemistry (2015) | Category: Engineering chemistry and chemistry of silicates | 1 | Recommended year of study:1, Recommended semester: Summer |