| Course title | Pharmacochemistry |
|---|---|
| Course code | UOCHT/C840 |
| Organizational form of instruction | Lecture |
| Level of course | Bachelor |
| Year of study | 3 |
| Semester | Winter |
| Number of ECTS credits | 5 |
| Language of instruction | Czech |
| Status of course | Compulsory |
| Form of instruction | Face-to-face |
| Work placements | This is not an internship |
| Recommended optional programme components | None |
| Lecturer(s) |
|---|
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| Course content |
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Object of pharmaceutical chemistry, basic notions - pharmacology, pharmacognosy, galenic pharmacy, medicinal drug, form of medicinal drug. Basic principles of general pharmacology - way of administration, fate of drug in organism: absorption, transport and distribution, metabolism (bio-transformations - oxidation, reduction, hydrolysis, conjugation, non-enzymatic transformations), excretion. Effects of medicinal drugs - specific and non-specific effect - relationships between structure and effect. Problems of research and development of new pharmaceuticals. European and Czech Pharmacopoeias, classification of drugs from pharmacological standpoint. General anaesthetics - mechanism of action. Syntheses of fluorine-containing inhalation anaesthetics (halothane), general intravenous anaesthetics (thiopental). Hypnotics and sedatives - effect and application. Syntheses of selected hypnotics of the 1st to 3rd generations.:
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| Learning activities and teaching methods |
| Monologic (reading, lecture, briefing), Dialogic (discussion, interview, brainstorming) |
| Learning outcomes |
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Strategy for Organic Drug Synthesis and Design.
Absolvents are Able Applicate Strategy for Organic Drug Synthesis and Design. |
| Prerequisites |
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KOCH/C008 - Organic chemistry I KFCH/C014 - Principles of Physical Chemistry
UOCHT/C008 and UOCHT/C511 |
| Assessment methods and criteria |
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Oral examination, Written examination
Understanding and active knowledge of Basic organic synthesis. |
| Recommended literature |
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| Study plans that include the course |
| Faculty | Study plan (Version) | Category of Branch/Specialization | Recommended semester | |
|---|---|---|---|---|
| Faculty: Faculty of Chemical Technology | Study plan (Version): Chemistry and Technical Chemistry (2016) | Category: Engineering chemistry and chemistry of silicates | 3 | Recommended year of study:3, Recommended semester: Winter |
| Faculty: Faculty of Chemical Technology | Study plan (Version): Farmacochemistry and Medicinal Materials (2016) | Category: Engineering chemistry and chemistry of silicates | 3 | Recommended year of study:3, Recommended semester: Winter |
| Faculty: Faculty of Chemical Technology | Study plan (Version): Chemistry and Technical Chemistry (2013) | Category: Engineering chemistry and chemistry of silicates | 3 | Recommended year of study:3, Recommended semester: Winter |
| Faculty: Faculty of Chemical Technology | Study plan (Version): Farmacochemistry and Medicinal Materials (2014) | Category: Engineering chemistry and chemistry of silicates | 3 | Recommended year of study:3, Recommended semester: Winter |
| Faculty: Faculty of Chemical Technology | Study plan (Version): Farmacochemistry and Medicinal Materials (2013) | Category: Engineering chemistry and chemistry of silicates | 3 | Recommended year of study:3, Recommended semester: Winter |
| Faculty: Faculty of Chemical Technology | Study plan (Version): Chemistry and Technical Chemistry (2015) | Category: Engineering chemistry and chemistry of silicates | 3 | Recommended year of study:3, Recommended semester: Winter |
| Faculty: Faculty of Chemical Technology | Study plan (Version): Farmacochemistry and Medicinal Materials (2015) | Category: Engineering chemistry and chemistry of silicates | 3 | Recommended year of study:3, Recommended semester: Winter |
| Faculty: Faculty of Chemical Technology | Study plan (Version): Chemistry and Technical Chemistry (2014) | Category: Engineering chemistry and chemistry of silicates | 3 | Recommended year of study:3, Recommended semester: Winter |