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Course info
UECHI / C030A
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Course description
Department/Unit / Abbreviation
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UECHI
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C030A
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Academic Year
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2019/2020
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Academic Year
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2019/2020
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Title
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Bioengineering
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Form of course completion
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Examination
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Form of course completion
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Examination
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Accredited / Credits
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Yes,
6
Cred.
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Type of completion
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Combined
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Type of completion
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Combined
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Time requirements
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Lecture
4
[HRS/WEEK]
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Course credit prior to examination
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No
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Course credit prior to examination
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No
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Automatic acceptance of credit before examination
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No
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Included in study average
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YES
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Language of instruction
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English
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Occ/max
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Automatic acceptance of credit before examination
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No
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Summer semester
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0 / -
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0 / -
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0 / -
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Included in study average
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YES
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Winter semester
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0 / -
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0 / -
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0 / -
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Repeated registration
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NO
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Repeated registration
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NO
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Timetable
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Yes
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Semester taught
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Winter + Summer
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Semester taught
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Winter + Summer
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Minimum (B + C) students
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not determined
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Optional course |
Yes
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Optional course
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Yes
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Language of instruction
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English
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Internship duration
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0
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No. of hours of on-premise lessons |
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Evaluation scale |
A|B|C|D|E|F |
Periodicity |
každý rok
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Periodicita upřesnění |
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Fundamental theoretical course |
No
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Fundamental course |
No
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Fundamental theoretical course |
No
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Evaluation scale |
A|B|C|D|E|F |
Substituted course
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KCHI/C030A
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Preclusive courses
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N/A
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Prerequisite courses
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N/A
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Informally recommended courses
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N/A
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Courses depending on this Course
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N/A
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Histogram of students' grades over the years:
Graphic PNG
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XLS
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Course objectives:
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The course covers the principles of biotechnologies from a chemical engineering point of view. The emphasis is given on examining the systems and components that are common to most or all biotechnology production processes.
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Requirements on student
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final project - 60% oral exam - 40%
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Content
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Biotechnology - an interdisciplinary pursuit. A contribution of Bioengineering to Biotechnology. What is Bioengineering? Kinetics of enzyme-catalyzed reactions. Simple enzyme kinetics with one and two substrates. Kinetics of substrate utilization, product yield, and biomass production in cell cultures. Overall kinetics in cases of chemical-reaction-mass-transport interaction. Design and analysis of biochemical reactors. The ideal continuous-flow stirred-tank reactor. The ideal plug-flow tubular reactor. Residence-time distributions. Dispersion models for nonideal reactors. Transport phenomena in microbial systems. Bioreactors. Microbial bioreactors. Non-microbial cell culture systems. Enzyme bioreactors. Relationships between batch and continuous biological reactors. General description of stirred vessel bioreactor. Mechanics of fluid flow and gas dispersion in stirred vessel. Experimental design, parameter optimatisation, scaling-up. Bubble column bioreactors. Hydrodynamics. Models of bubble columns. Biochemical loop reactors - propeller (PLR) and air-lift loop reactors (ALR). Bioreactors second generation. Immobilized cell/enzyme bioreactors. Membrane bioreactors. Downstream processing operations. Precipitation. Crystallization. Centrifugation. Membrane separations. Chromatographic methods in bioprocessing. Supercritical fluid extraction. Special problems of bioreactors. Bioreactor and catalyst design for fermentation processes. Costs. Sterilization and preservation in bioprocessing, safety in biotechnology. Fundamentals of computer control in fermentation processes. Biotechnology in waste water treatment and environmental technologies.
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Activities
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Fields of study
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Guarantors and lecturers
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Literature
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Basic:
Doran P.M. Bioprocess Engineering Principles. Academic Press Limited, London, 1995.
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Further literature:
Ratledge C., Bjorn K. Basic Biotechnology. Cambridge Univ. Press, 2001.
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Further literature:
Lydersen B.K., D'Elia N.A., Nelson K.M. Bioprocess Systems, Equipment and Facilities. John Wiley & Sons, 1994.
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Prerequisites - other information about course preconditions |
- |
Competences acquired |
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Teaching methods |
- Monologic (reading, lecture, briefing)
- Work with text (with textbook, with book)
- Methods of individual activities
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Assessment methods |
- Oral examination
- Written examination
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